WestChina-Frontier

Special Treatment: Evaluation of Ophthalmic Drugs Inhalation Formulation Study of Radioactive Isotope Labeled Drugs Neuropsychic Drug Studies Pediatric Drug Studies

Safety Evaluation: Safety Pharmacology General Toxicity Genetic Toxicology Reproductive and Development Toxicology Studies Carcinogenicity Test Drug Dependence Test Immunogenicity and Immunotoxicity Studies

Pharmacodynamic Evaluation: Eye disorder models Respiratory disorder model Tumor models Metabolic disorder models Neuropathy models Immuno-inflammatory disorder model Cardiovascular disorder models Other animal models

PK/TK Studies: In vivo PK study of drugs Out vitro PK study of drugs Plasma protein binding study Caco-2 cell permeability and absorption study Drug-drug interaction study In vivo PK study of drugs

Pharmacodynamic studies

WestChina-Frontier has established a professional team consisting of pharmacologists, physiologists, radiologists, surgeons, laboratory animal veterinarians, and laboratory animal technicians for studies in laboratory animal disease models;

the professional team carries out studies in disease animal models and provides technical services; all models for efficacy evaluation of new drugs have been validated to ensure their stability and reliability.

Service Offerings

Eye disorder models

corneal injury; acute ocular hypertension; choroidal neovascularization (CNV); dry eye.
Neuropathy models: migraine model

acetic acid-induced writhing test model; formalin-induced acute, chronic inflammatory pain; incision pain mode
Respiratory disorder model

pulmonary fibrosis; asthma; pulmonary injury; acute pneumonia; chronic obstructive pulmonary disease (COPD)
Metabolic disorder models

gout model; diabetes mellitus model;
glucolipid metabolic disorders models; mouse obesity model;
Immuno-inflammatory disorder model

ulcerative colitis model; gastrointestinal tract food allergy model;
rheumatoid arthritis; multiple sclerosis;
Cardiovascular disorder models

heart failure model; reperfusion model for left ventricle myocardial ischemia
Other animal models

alopecia model; skin damage repair model
Tumor models

murine/human-derived tumor models