WestChina-Frontier has established a GLP-compliant mature technical system for evaluation of drug dependence, a platform for pharmacodynamic study of analgesics, and an integrated technology platform to monitor the cardio-pulmonary functions and ECG of large animals on anesthetics.
Natural withdrawal, precipitation withdrawal and conditioned place preference (CPP) test models in rodents;
Self-administration, drug discrimination and sensitization test models in rodents;
Dependence evaluation in large animals (monkeys);
Construction and efficacy evaluation of morphine addiction model in large animals (monkeys);
Integrated monitoring system for synchronous detection of ECG, blood pressure, respiratory rate, and EEG of Beagle dogs, monkeys, and miniature pigs.
Addressing the challenges in non-clinical evaluation of surgical anesthesia/analgesics—simulating clinical general anesthesia and comprehensive monitoring during surgery
Physical stimulation induced pain animal model;
Inflammatory pain animal model;
Neuropathic pain animal model;
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